Our Team

Mattias Kyhlstedt

CEO and Founder

Mattias is leading market access activities at Synergus.
He has over 20 years of experience from the Medical Device Industry. Mattias started his career within quality and regulatory and has held several positions within production, quality, logistics and R&D in a global medical device corporation specialized in intensive care. During the years, Mattias also developed a very unique and extensive reimbursement and market access knowledge and is today combining his regulatory and business development insights when consulting medical device companies worldwide on how to develop their reimbursement and regulatory strategies. He has considerable experience in development of Pan-European reimbursement strategies for medical device companies. Mattias is also a frequent speaker at international reimbursement and regulatory conferences.


Tim Spelman, MD, PhD

Senior Scientist

Dr Tim Spelman is a biostatistician of 16 years’ experience having worked with a variety of national and international research organisations including the Australian Bureau of Statistics, Melbourne Brain Centre, the Burnet Institute, Monash University’s Department of Epidemiology and Preventive Medicine, the Victorian Infectious Diseases Service, the Peter Doherty Institute for Infection and Immunology, the Department of Health the United Nations Programme on HIV/AIDS, Flinders University  and Deakin University among others. He has over 135 publications in infectious diseases, immunology, multiple sclerosis, neurology, population health, epidemiology and virology. He is currently senior advising statistician to the Lancet and senior advising statistician to the Economics Sub-Committee of the Pharmaceutical Benefits Advisory Committee.

He is currently a member of the editorial board of the Journal of the International AIDS Society and the current guest Lead Editor for the Biomed International Research Journal. He is also currently a member of the international Tysabri Observation Programme steering committee and a member of the Data Management Sub-Committee for the Big MS Data Network International Collaborative of Multiple Sclerosis data registries. He is currently a member of the Data and Safety Monitoring Committee (DSMC) of the NICE-GUT randomised clinical trial of nitazoxanide for treating Aboriginal children hospitalised for gastroenteritis in the Northern Territory as well as working previously as a clinical trial statistician. He has presented research at many international conferences and workshops and run statistical training courses for researchers and clinicians in Australia, Europe, the United States, South-East Asia and Southern Africa and has collaborated extensively with research groups globally including the UN, WHO, MSF, the Karolinska Institute, Oxford and Harvard. He has also extensive clinical experience, and currently practices as a General Practitioner. He also has extensive management experience, supervising both junior statisticians and epidemiologists in addition to trainee clinicians. 


Michel Verhasselt, MBA

Senior Market Access Consultant

Michel is leading market access and health economic activities in France and Belgium.
Michel is a knowledgeable and experienced professional in the field of health economics, HTA, DRG coding and reimbursement with over 20 years experience gained from working on both the international and local level for the medical device industry, healthcare providers and insurance companies. He brought his expertise to renowned companies like Johnson & Johnson, Baxter, Linde, Allianz / Mondial Assistance and Edwards Lifesciences. He has successfully managed funding & reimbursement of breakthrough innovations like the Transcatheter Aortic Valve (TAVI) in France, Benelux and Switzerland obtaining premium pricing and adequate DRG coverage. He developed market access expertise in various therapy areas: renal products, medical gas (Oxygene, INO, anaesthesia, wound healing, pain), respiratory including asthma and COPD, interventional cardiology, critical care diagnostic devices, vascular and cardiac implants. He has an M.B.A in Business Management and Healthcare Economics at Lille Catholic University in France.


Vladica M. Veličković, MD, MSc, PhD(c)

Health Economist

His primary responsibilities are project management in the field of evidence synthesis, health economics and outcome research. Vladica Veličković, is a Doctor of Medicine, Ph.D. candidate in the field of health service research with the focus in HTA and health economics. He is former teaching assistant at the Public Health Department, Faculty of Medicine University of Niš, Serbia and he recently completed visiting and studying period at UMIT at the Institute of Public Health, Medical Decision Making and Health Technology Assessment, Hall in Tirol, Austria. Over and above, he has a five-year experience of working in pharmaceuticals companies at sales force: at outsourcing company Goodwill pharma and big pharma company Les Laboratories Servier. His research field of interest is health service research, especially HTA and health economics. He has a strong biostatistics background (advanced user with STATA statistical package) and he mastered the decision analytic modelling techniques as State Transition modelling but also Discrete Event simulations and Agent-Based modelling.


Huseyin Aytug, PhD

Market Access Consultant

Dr. Huseyin Aytug is a Data Scientist with a background in Economics. He received his M.A (2010) and Ph.D. (2013) both in International Economics from University of California-Santa Cruz, US. He has extensive experience of statistical data analysis in macroeconomics, international finance, micro-econometrics and machine learning. He previously worked at Central Bank of Turkey and Gulf Monetary Council as an Economist. He is an author and co-author of numerous journal and conference papers, as well as three book chapters. He also worked as a Senior Lecturer at Bahrain Institute of Banking and Finance and taught Economics, Math, Statistics and Econometrics classes. His main responsibility includes big data/machine learning and real world data projects. He is also involved with market access projects to offer our clients advance applied econometrics and biostatistics methods to break the barriers of adopting new technologies.


Claire Moreau, PharmD

Market Access, Pricing & Reimbursement Consultant

Claire is primary developer of reimbursement dossiers for medical devices in France and Belgium.
Claire is a pharmacist by training and recognized as a medical writer expert. She has extensive experience of reimbursement submissions gained from working at French level for health product industries. During the last 15 years, she brought her expertise to companies like Bristol Myers Squibb, Sanofi-Aventis, Baxter and Leo Pharma in roles encompassing regulatory affairs, pricing & reimbursement and market access). She also worked as a consultant at Carré Castan Consultants, as Project Manager at AFSSAPS/ANSM and as a pharmacist at AP-HP (public hospital in Paris). She has successfully managed funding & reimbursement of drugs and medical devices in France and negotiations with Health Authorities. She has also contributed to define the best market access strategies and developed market access expertise in various therapy areas (renal therapy, anaesthesia, cardiology, oncology, nutrition, immunology, pulmonology or rare disease).


Sun Sun, MSc, Phd

Health Outcomes Researcher / Health Economist

Sun Sun is involved in health economic projects, and leading patient-reported outcomes activities at Synergus. She is also currently affiliated to the Health outcomes and Economic Evaluation Research Group at Karolinska Institutet (from July 2014).
Previously, Sun Sun has served as health economist at Stockholm County Coucil (2006-2014, 8 years), where she gain extensive knowledge in health-related quality of life, and broad expertise in application of epidemiological and health economics methods in the context of Swedish health care system. Mean while, Sun Sun was also affiliated to both the Health Economics Research Group at Department of Learning, Informatics, Management and Ethics and Equity and Health Policy Research Group at Department of Public Health, at Karolinska Instituet.
Sun Sun has PhD in Health Economics, her PhD project is based on a cooperation between Karolinska Institutet in Sweden, Nanjing Medical University and Minsitry of Health in China. In the research project, more than 120 000 face-to-face interviews were carried out, on a representative sample of the Chinese general population. The population norm for EQ-5D in China was established, and a value set for EQ-5D health states was tested. As one of the project initiator, Sun Sun was involved in the projects in different aspects at all stages, including study design, project managment, field work, data analysis and other scientific works.
Sun Sun has been a EuroQol member since 2008 (Scientific body for the EQ-5D instrument) and a member to the Swedish Health Economics Association since 2010. She has advance knowledge in health related-quality of life and health outcomes research. She is also skilled in data management, data analysis, planning and conducting health economics-related studies.


Rongrong Zhang, MSc

Associate Evidence Synthesis Consultant

Rongrong has extensive experience with systematic literature reviews, meta-analyses, and development of reimbursement and HTA dossiers/value communication documents – having authored publications of systematic reviews in various healthcare settings. She has taken several specialized courses in health economics and continues to pursue deeper knowledge in statistical methods and in the health economics and outcomes research arena. With a M.Sc. in Bioentrepreneurship from Karolinska Institutet and a B.Sc. in Pharmaceutical Science as a background, she has hands-on experience in the Chinese healthcare system and in-depth knowledge of both the pharmaceutical and medical device market. For example, she has worked directly in a high-tier hospital in Shanghai for five years; was a Consultant for ACCESS Health International, founded by Prof. Emeritus William Haseltine; and performed services as an Intermediary Product Manager at Roche Pharmaceuticals in Shanghai.


Audrey Ortiz, PharmD, MSc

Health Economics Analyst

Audrey is involved in healh economic projects in France and Belgium.
She started her training as engineer, in preparatory class for “Grandes ecoles” but ended to hold a Pharm D and a Master Degree in Health Economics from Paris-Dauphine University.
She has work experiences in big pharma and mid-sized companies. Involved in activities in departments as diverse as production, quality, regulatory affairs, pharmacovigilance, regional market access and economics affairs, she has developed a good understanding of pharmaceutical company operations. Because of its experience in AGEPS, AP-HP body responsible for evaluation and procurement of medicines and devices, she had been made aware of the requirements for making an health product available in AP-HP hospitals.


Natalia M. Stelmaszuk, BSc, MSc

Research Analyst

Natalia is involved in epidemiological activities including biostatistical analysis of health care data sets and development of value documentation for medical devices.
She holds a B.Sc. degree in Public Health from the Medical University in Warsaw, Poland. In 2014 she finished her master program at Karolinska Institutet in Stockholm, Sweden with a Master of Science degree in Epidemiology.
During the course of studies she gained a great knowledge on a broad spectrum of public health issues and developed her skills of analyzing and reflecting on those problems. Program of Public Health at Warsaw Medical University included courses in biology, medicine and biomedicine that broaden her knowledge providing her with necessary public health skills. During the master’s program at Karolinska Institutet, however, she acquired an in-depth knowledge of epidemiological and biostatistical methods, data acquisition and management, and methods for outcome assessment. She worked within CAHRES (Cancer And HoRmonEs in Sweden) project analyzing Swedish breast cancer database for her master thesis project. She has experience with the most common statistical packages (SPSS, SAS and STATA).


Cristina Rao, MSc

Market Access Analyst

Cristina Rao is involved in market access activities.
She holds a Bachelor’s Degree in Economics, Markets and Institutions from the University of Bologna and a Double Master’s Degree in Health Economics and Management from the University of Bologna and the Management Center Innsbruck. She gained an in-depth knowledge about stakeholder analysis and financing options of European healthcare systems. She is also confident with the use of the main statistical and econometric methods for health economics. She is fluent in Italian and English.


Vasily Lukyanov, MSc

Health Economics Analyst

He has 7 years of experience in life science industry and was developing business in the area of pharmaceutical market intelligence and contracted drug discovery. Additionally, prior to joining Synergus, he worked at a boutique market access consultancy, conducting budget impact modelling (e.g. intra operative neural monitoring) for the Russian market. Apart from BSc degree in Pharmacy from Moscow Medical Academy, Vasily pursued MSc degree in Health Economics. During the course of study at Erasmus University Rotterdam, he acquired valuable and modern knowledge on concepts and tools of economic analysis of health care, including the analysis of the peculiar functioning of health care markets and the economic evaluation of health care programs and interventions. Vasily has university level of programming in STATA , and is developing his expertise in Winbugs and R.


Emily McIlwaine, PhD

Market Access Analyst

Emily is responsible for market access activities related to the United Kingdom. Emily has a background in molecular biology, genetics and biochemistry and gained her BSc degree at the University of Glasgow. Following this, Emily completed MRes and PhD degrees at Newcastle University in the field of translational medicine. This provided her with an in-depth understanding of scientific methodology and data analysis. After gaining her PhD she worked as a medical writer for a market access company in the UK which gave her exposure to professional writing, editing and market access.


Vivien Boldis, MSc

Market Access and Evidence Analyst

Vivien is involved in market access activities and health economics projects. Vivien has a background in Health Care Science and gained her BSc degree at Semmelweis University, Budapest, Hungary. She also holds a MSc degree in Public Health with specialization in Health Economics from Umeå University, Sweden. During her MSc she worked with the Swedish Health on Equal Terms survey (Hälsa på lika villkor) which gave her in-depth knowledge in data analysis. 


Mo Wang

Research Analyst

Mo Wang has a background in psychology and received her BSc degree at Stockholm University in Sweden. She also has PhD in Medical Science from Division of Insurance Medicine, Karolinska Institutet in Sweden. Her PhD project is about sickness absence and subsequent psychiatric morbidity and suicidal behavior by using population-based Swedish registers. Mo Wang previously worked as a post-doc at Karolinska Institutet and she was involved in several different projects regarding work disability in relation to acute myocardial infarction and lumbar spine surgeries. Mo Wang has extensive work experience with epidemiological studies, study design, register data, data management and data analysis. She also has good knowledge in Swedish social insurance system and is skilled in several common statistical packages (SPSS, SAS and R). 


Nyree de Quidt

Project Coordinator and Team Assistant

Nyree helps to coordinate Synergus’ projects and provides administrative support to the team. She has a BA in Social Policy and Administration and experience as a Coordinator and Relationship Manager in the non-profit and social sectors.